• Dietary advanced glycation end-products and colorectal cancer risk in the European prospective investigation into cancer and nutrition (EPIC) study 

      Aglago, Elom K.; Mayén, Ana-Lucia; Knaze, Viktoria; Freisling, Heinz; Fedirko, Veronika; Hughes, David J.; Jiao, Li; Eriksen, Anne Kirstine; Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Rothwell, Joseph A.; Severi, Gianluca; Kaaks, Rudolf; Katzke, Verena; Schulze, Matthias B.; Birukov, Anna; Palli, Domenico; Sieri, Sabina; de Magistris, Maria Santucci; Tumino, Rosario; Ricceri, Fulvio; Bueno-De-Mesquita, Bas; Derksen, Jeroen W.G.; Skeie, Guri; Gram, Inger Torhild; Sandanger, Torkjel M; Quirós, J. Ramón; Lujan-Barroso, Leila; Sánchez, Maria-Jose; Amiano, Pilar; Chirlaque, María-Dolores; Barricarte, Aurelio; Johansson, Ingegerd; Manjer, Jonas; Perez-Cornago, Aurora; Weiderpass, Elisabete; Gunter, Marc; Heath, Alicia K.; Schalkwijk, Casper G.; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-08)
      Dietary advanced glycation end-products (dAGEs) have been hypothesized to be associated with a higher risk of colorectal cancer (CRC) by promoting inflammation, metabolic dysfunction, and oxidative stress in the colonic epithelium. However, evidence from prospective cohort studies is scarce and inconclusive. We evaluated CRC risk associated with the intake of dAGEs in the European Prospective ...
    • Dietary intake of advanced glycation endproducts and risk of hepatobiliary cancers: A multinational cohort study 

      Ana-Lucia, Mayén; Aglago, Elom K.; Knaze, Viktoria; Cordova, Reynalda; Schalkwijk, Casper G.; Wagner, Karl-Heinz; Aleksandrova, Krasimira; Fedirko, Veronika; Keski-Rahkonen, Pekka; Leitzmann, Michael F.; Katzke, Verena; Srour, Bernard; Schulze, Matthias B.; Masala, Giovanna; Krogh, Vittorio; Panico, Salvatore; Tumino, Rosario; Bueno-de-Mesquita, Bas; Brustad, Magritt; Agudo, Antonio; López, María Dolores Chirlaque; Amiano, Pilar; Ohlsson, Bodil; Ramne, Stina; Aune, Dagfinn; Weiderpass, Elisabete; Jenab, Mazda; Freisling, Heinz (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-25)
      Advanced glycation endproducts (AGEs) may contribute to liver carcinogenesis because of their proinflammatory and prooxidative properties. Diet is a major source of AGEs, but there is sparse human evidence on the role of AGEs intake in liver cancer etiology. We examined the association between dietary AGEs and the risk of hepatobiliary cancers in the European Prospective Investigation into Cancer ...
    • Plasma concentrations of advanced glycation end-products and colorectal cancer risk in the EPIC study 

      Aglago, Elom K.; Schalkwijk, Casper G.; Freisling, Heinz; Fedirko, Veronika; Hughes, David J.; Jiao, Li; Dahm, Christina C.; Olsen, Anja; Tjønneland, Anne; Katzke, Verena; Johnson, Theron; Schulze, Matthias B.; Aleksandrova, Krasimira; Masala, Giovanna; Sieri, Sabina; Simeon, Vittorio; Tumino, Rosario; Macciotta, Alessandra; Bueno-De-Mesquita, Bas; Skeie, Guri; Gram, Inger Torhild; Sandanger, Torkjel M; Jakszyn, Paula; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Barricarte, Aurelio; Perez-Cornago, Aurora; Mayén, Ana-Lucia; Weiderpass, Elisabete; Gunter, Marc J.; Heath, Alicia K.; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-29)
      Advanced glycation end-products (AGEs) are a heterogeneous group of compounds formed by the non-enzymatic reaction between amino acids and reducing sugars, or dicarbonyls as intermediate compounds. Experimental studies suggest that AGEs may promote colorectal cancer, but prospective epidemiologic studies are inconclusive. We conducted a case–control study nested within a large European cohort. Plasma ...